Broccoli Max. 90 Vcaps

PRESENTATION: 90 vegetable capsules

INGREDIENTS: Dry extract of Broccoli (Brassica Oleracea L (in high concentration of active principles; Sulforaphane and Indole-3-Carbinol), Coating agent (hydroxypropylmethylcellulose), anti-caking agents (magnesium salts of fatty acids and silicon dioxide), and Black Pepper Extract (Piper nigrum L).

DIRECTIONS FOR USE: Take one capsule, three times a day, 15 minutes before meals. 100.5 mg of Sulforaphane (in Broccoli extract 1000.5 mg per daily intake). 55.25 mg of Indole-3-Carbinol (in Broccoli extract 1105 mg per daily intake).

TRADITIONAL USE OF ITS COMPONENTS:

A family of vegetables is a source of at least two compounds with recognized effectiveness in cancer treatment: sulforaphane and indole-3-carbinol. These act by stopping the growth of cancer cells, blocking angiogenesis (the formation of new blood vessels necessary for tumor growth), and promoting apoptosis (programmed death of tumor cells).

SULFORAPHANE

Sulforaphane is a natural organic compound that is part of isothiocyanates, molecules that contain a sulfur atom. Sulforaphane is found in cruciferous vegetables such as broccoli, kale, Brussels sprouts, cabbage, bok choy, watercress, arugula, and kale, i.e., plants of the Brassicaceae family. It has been shown to provide many health benefits. Among its many properties:

It has anticancer properties.

Different studies have demonstrated its protective role, within a healthy diet and lifestyle, against some types of cancer such as breast, uterine, prostate, and internal organ cancers like liver, colon, kidneys, and intestines. These anticancer properties are enhanced by its content of vitamin A (in the form of beta-carotenes), C and E, folic acid, amino acids, zinc, iron, and potassium.

Inhibition of angiogenesis and metastasis

Angiogenesis is the process by which new blood vessels are formed and is essential for the growth and expansion of cancer. Sulforaphane can inhibit angiogenesis, thus limiting the supply of nutrients and oxygen to cancer cells. Additionally, it can decrease metastasis, which is the spread of cancer cells to other organs and tissues.

INDOLE-3-CARBINOL

Indole-3-carbinol (I3C) is a phytochemical found in vegetables of the cruciferous family (broccoli, cauliflower, and Brussels sprouts). It is important as an antioxidant and anticancer agent, known since the 1960s for its effect on carcinomas caused by chemical toxins. Currently, we know that indole-3-carbinol can modulate estrogen metabolism.

Indole-3-carbinol appears to work in several ways:

1. Facilitates the conversion of estrogen into a less cancer-stimulating form.
2. Partially blocks the effects of estrogen on cells.
3. Directly eliminates or inhibits cancer cells.
4. Reduces levels of free radicals, which can stimulate cancer development by damaging DNA.

A 4-week double-blind, placebo-controlled study with 57 women found that a minimum dose of 300 mg of I3C per day might be necessary to reduce the risk of estrogen-induced cancer. Another study found benefits with 400 mg of I3C per day.

Several in vitro and in vivo studies have demonstrated that it inhibits up to 90% of the growth of tumor cells characterized by the presence of estrogen receptors. It has also proven to be a potent chemopreventive agent for hormone-dependent cancers such as breast, cervical, or prostate cancer. It also inhibits cell growth in breast carcinomas characterized by the absence of estrogen receptors due to its antioxidant action.

In cancer prevention and treatment, it has been proven through nutritional methods that Indole-3-Carbinol and sulforaphane are especially indicated for the following types of cancer:

Lung cancer, partially neutralizing nitrosamines (carcinogenic compounds) present in cigarette smoke. "Hormonal" cancers such as breast and endometrial cancer, opposing estrogens and thus blocking their progression. Stomach cancer, activating antioxidant enzymes in the gastric mucosa, thus protecting it from damage that the H. pylori bacterium could cause to its DNA.

It has been demonstrated that in countries where the consumption of cruciferous vegetables is significant, the incidence of lung, colon, breast, and prostate cancers is much lower.

Indole-3-carbinol is also distinguished by its action against the body's chemoresistance, thus reducing chemotherapy sessions.

Another outstanding property of Indole-3-Carbinol and sulforaphane is their ability to neutralize carcinogenic substances, protecting DNA from chemical damage and thus reducing the risk of developing cancer related to these sources of contamination.

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